SECTION A - MULTIPLE CHOICE
QUESTIONS 10 MARKS
Instructions
·
This section consists of TEN (10) questions
·
Encircle the letter of the most correct answer
·
There is only one correct answer
·
One (1) mark will be awarded for each correct answer
1. Which of the following alkaloids have oxytocic
effect?
a.
Vinblastine
b.Tropane c. Ergometrine d. Vincristine e. Pilocarpus
2. Which
of the following crystals occurs Occur as feathery-like aggregates or
sphaerocrystalline masses in the cells of many of the Rutaceae and in isolated
plant of other families........
a.
Calcium oxalate b. Silica crystals
c. Calcium carbonate crystals d. Hesperidin and Diosmin e. Cystolith
3. The following is correct about Cocoa ?
a.
Cocoa kernels contain 0.9 - 2%
theobromine and the husk 0.9- 2.98% of this alkaloid
b.
Cocoa kernels contain 0.19 - 3% theobromine
and the husk 0.19- 2.98% of this alkaloid
c.
Cocoa kernels contain -0.9 - 3%
theobromine and the husk 0.19- 3.0% of this alkaloid
d.
The seed also contains 0.5 – 0.6%
caffeine, cocoa fat/butter, condensed tannins and volatile compounds
e.
Cocoa kernels contain 0.9 - 3%
theobromine and the husk 0.19- 2.98% of this alkaloid
4. Which of the following drug is commonly known
as Indian snske root?...........
a.
Ergot b. Rhubarb c. Aloe d.
Rauwolfia e. Vinca
5. Omega 3
fatty acid is among the constituents of the following fixed oil.....
a) Olive
oil b. Castor oil c. Coconut oil d. Cold liver oil e. Peanut oil
6. An
example of steroidal alkaloids is .........................?
a. Purines
b. Connesine c. Caffeine d. Theophylline e. Theobromine
7. Derivatives
of lysergic acid is the constituent of which medicinal plant ………………..
a.
Cascara b.
Rhubarb c. Nux vomica d. Ergot e. Calabar beans
8. Which of the following is an alkaloid with a
purine skeleton?
a.
Hygrine b. Ephedrine
c. Strychnine d. Theobromine
e.Solanidine
9. An example of medicinal plant which contain
Calcium carbonate cryatstals is .........
a.
Lemon b. Cardamom seeds c. Cannabis sativa d. Oranges e. Belladonna
10. Which compound required long storage in order to avoid vomiting in
fresh bark of Cascara?
a.
Aloe-emodin
b. Rhein c. Resins d. Barbaloin e. Anthrones
SECTION B: MULTIPLE TRUE FALSE QUESTIONS 10 MARKS
Instructions:
·
This section consists of four (4) questions with five (5) option each
·
Write the word TRUE and NOT letter ‘T’ for a correct statement and
FALSE, NOT letter ‘ F ‘ for incorrect statement in the space provided for each
option
·
All responses should be in CAPITAL letters
·
Half (1/2) will be awarded for each correct
response
·
Responses with letters ‘T’ and ‘F’ will not be awarded any mark
·
There will be a penalty of half (1/2) of the
allocated marks for response in small letters
1.
Coffee ..............
A.
............... family sterculiaceae
B.
............... contain 0.9 - 3% theobromine
C. ............... For heart
and kidney tonic
D. ................ family
rubiaceae
E.
............... used in combinations with antipyretics
and analgesics, cold and flu medication
2.
Regarding squill .......
A.
............... family Liliaceae
B.
............... Scillaren A is an amorphous mixture of glycosides
C.
................ Scillaren B is crystalline in form
D.
............... The white squill contains Scillirosides in
addition to the other glycosides
E.
............... White squill is used as
diuretics agents
3.
Classification
of the volatile oil basis on their functional groups...............
A. ............... Oxide volatile oils e.g. rosemary oil
B.
................ Phenolic volatile oils e.g camphor
C.
............... Phenolic
ether volatile oils e.g. fennel oil
D.
............... Aldehydic
volatile oils e.g. lemon oil
E.
............... Hydrocarbon
volatile oils e.g coriander oil
4.
Regarding constituents of Calabar
Beans.............
A.
............... Geneserine
B.
............... Physostigmine
C.
............... Strychnine
D.
...............Ξ±-colubrine
E.
............... Reserpine
SECTION
C: MATCHING ITEM QUESTIONS 10 MARKS
Instructions:
·
This section consists of two (2) questions of matching with five (5)
options each
·
Match the items in column B with those in column A by writing the
letter of the correct response in the space provided on each option. USE
CAPITAL LETTERS
·
Each correct response is awarded one (1) mark
·
Each item from column B is used only once
1. Match the terms in column A to corresponding meaning column B 5 MARKS
|
COLUMN
A
|
COLUMNN
B
|
|
1 ............... Pilocarpus
|
A. C.arabica
|
|
2 ............... Vinca
|
B. R.serpentine
|
|
3 ............... Ergot
|
C. P.jaborandi
|
|
4 ............... Calabar
|
D. C.roseus
|
|
5 ...............Rauwolfia
|
E. C.officinalis
|
|
|
F. P.venonosum
|
|
|
G. C.purpurea
|
2. Match the terms in column A to corresponding
meaning column B 5 MARKS
|
COLUMN
A
|
COLUMN
B
|
|
1 ............... Potassium Mercuric Iodide
|
A. Gives yellow crystalline precipitates
|
|
2 ............... Potassium Iodide + bismuth nitrate
|
B. Give buff coloured precipitates
|
|
3 ............... Iodine-Potassium Iodide
|
C. For ergot alkaloids and gives a blue
colour
|
|
4 ............... Picric Acid
|
D. Produces white or yellow colour precipitates
|
|
5 ............... Tannic Acid solution
|
E. Produces brown or reddish-brown
precipitates
|
|
|
F. For solanaceous alkaloids and give a violet colour
|
|
|
G. Produces orange red precipitates
|
SECTION
D: SHORT ANSWER QUESTIONS 40 MARKS
1.
A. Mention five chemical
properties of alkaloids
...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................
B. Alkaloids terminate with
the suffix-ine,their names may be derived from the:
§ Generic plant name -
§ Specific name of the plant –
§ Names of loved ones -
§ Common name of the plant –
§ Physiological action of the plant –
2.
Give definition of the following crude drugs:
a.
Cod-liver oil
……………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………..
b.
Lanolin
……………………………………………………………………………………………………………………………………..
c.
Lard
………………………………………………………………………………………………………………………………………
d.
Bees wax
………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………
e.
Spermaceti
……………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………..
3.
Mention five classification of
poisonous plant
...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................
4.
With examples mention five
general forms and size of crystals
...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................
5.
A. Enlist
four species that yield Aloe
………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………..
B.
Mention
two most important constituents of Aloes
…………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………..
6.
Outline
four stages of Stas-Otto Method of extraction of alkaloids
………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………..
7.
A. Outline two groups of cardiac
glycosides
..........................................................................................................................................................................................................................................................................................................................
B. what is the mechanism of
action of cardiac glycosides
…………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………..
8.
A. List the two (2) active
constituents of digitalis leaf
...........................................................................................................................................................................................................................................................................................................................
B. Mention the use of the
dried digitalis leaf
.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................
C.
State the storage condition of
digitalis leaf
........................................................................................................................................................
D.
What is required percentage moisture
contant for storage of digitalis leaf
........................................................................................................................................................
SECTION
E: GUIDED ESSSAY QUESTIONS 30 MARKs
1.
Explain
five methods of evaluation of crude drug
with the following protocol;
Organoleptic evaluation, Microscopic evaluation ,Chemical
evaluation, Physical evaluation
Biological evaluation
2.
Explain
three (3) medicinal plants in the group of gums/mucilage basing on Biological
source,chemical constituents and their uses in pharmacy
3.
Explain the
Hegnauer’s Classification, alkaloids
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